Oscar will lose his hands. This will be the second time this has happened to him; the first time was when a shady Director trespassed on his train and attacked him. So on top of this event bringing up all kinds of bad feelings about that again, Oscar will also lose his ability to work for the Fire Brigade and the Clinic. He may or may not go for replacement hands (really depends on what's on offer), but this should finally mean that he will properly focus on the fact that his body has been in bad shape since the Null attack and is now in even worse shape due to the Sorrow event that just happened. He'll acknowledge that he really needs to approach someone about maintenance soon. For this and possibly maybe replacement hands, he will more than likely seek out Alphys!

Since he won't be going about his daily business without hands, there won't be much opportunity to talk to him while he's in that state unless you see him between his apartment and the Lab or inside the Lab itself, where he might end up just sitting looking like a sad sack. He'll be calling Nick for assistance initially.